profiler

Profhilo

What is Profhilo?

Works Deep Within the Skin
Profhilo is a hyaluronic acid treatment that works deep within the skin to create plump, radiant skin. It achieves skin quality improvement through collagen and elastin production in the dermal layer, as well as remodeling (restructuring) of fibroblasts and adipocytes. In addition to stimulating collagen and elastin, it also activates adipose stem cells, helping to address the facial volume loss that occurs with aging. It slows down skin aging and maintains firmness and elasticity.

Natural Lifting Effect
Traditional hyaluronic acid injections have been used to fill in wrinkles or add volume to specific areas. Profhilo is unique in that after injection, it naturally spreads beyond the injection site. By diffusing deeply from fewer injection points, rather than simply filling wrinkles and sagging, it produces an effect where the entire skin becomes plumper and more youthful. Unlike conventional hyaluronic acid, Profhilo is highly fluid and soft, resulting in a natural-looking finish.

High Safety Profile
Profhilo is stabilized using a special thermal processing method. This patented technology makes the formulation safer and more stable. The product does not contain commonly used chemicals or biological agents, which means allergic reactions are unlikely, making it safe to use. Known as a "next-generation hyaluronic acid" or "hybrid hyaluronic acid," it is one of the most notable new injectable treatments available.

Long-Lasting Results
Because the effects are achieved through fundamental regeneration of skin cells, the results are long-lasting. With regular treatments, it is possible to maintain your skin's condition over time.

How Profhilo Works

Profhilo is injected in small amounts at shallow depths (10 points across the entire face), where it naturally penetrates and diffuses to affect the entire skin. Its effects extend from the epidermis to the dermis and adipose tissue, activating keratinocytes, fibroblasts, and adipocytes to promote collagen and elastin production. This triggers remodeling across all layers of the skin and subcutaneous tissue, improving not only skin texture and radiance but also restoring natural volume and firmness to aging skin, resulting in a lifting effect and wrinkle reduction. Additionally, by promoting skin turnover, accumulated dead skin cells and melanin pigment are shed, which can help brighten the complexion and improve skin clarity.

Recommended For

Facial Sagging and Wrinkles

Eye Area and Crow's Feet
The eye area includes several zones such as the crow's feet and upper and lower eyelids, and many people are concerned about wrinkles around the outer corners of the eyes. A major reason is that the skin becomes thinner with age, making wrinkles more likely to form. Profhilo uses a method of precise injection at 10 specific points, and it is also effective for the eye area.
By adding plumpness and elasticity to the eye area, it helps prevent fine lines and achieve a more youthful appearance.

Cheeks and Nasolabial Folds
When the cheeks lose moisture and elasticity and begin to droop, nasolabial folds (smile lines) become more prominent. Profhilo helps restore moisture and elasticity to the cheeks, lifting them and reducing the appearance of nasolabial folds. It is effective for natural rejuvenation and a lifting effect.

Mouth Area
Profhilo is primarily effective on the lower half of the face, making it also effective for sagging around the mouth. By increasing facial fat volume and restoring plumpness, sagging around the mouth is improved. For more significant improvement, combining it with hyaluronic acid fillers or thread lifts can also be effective.

Neck and Hand Care

Neck
Unlike the face, the neck is an area that is not covered by makeup, yet the skin is thin and tends to show signs of aging easily.
Horizontal neck wrinkles can be reduced with Profhilo, helping to achieve a healthier, more youthful appearance.

Hands
The backs of the hands are an area where bones and veins become more visible with age.
Injecting Profhilo into the backs of the hands creates natural firmness and radiance, helping to restore a youthful look to the hands.

Treatment Details

ResultsSome patients may notice results immediately after treatment, but the true effects appear after 3 to 4 weeks as skin remodeling (restructuring) progresses.
While results can be seen after a single session, having 2 treatments at 1 to 2 month intervals initially allows you to experience noticeable changes such as a lifting effect, skin tightening, and improved texture.
Results typically last 6 months to 1 year, so re-injection after 6 months or ongoing annual treatments can help maintain skin condition.
Treatment TimeAnesthetic cream application and waiting: approx. 30 minutes
Full face: 5 minutes
Neck only: 5 minutes
Backs of hands: 5 minutes
AnesthesiaNitrous oxide sedation or anesthetic cream recommended.
PainAs injections are administered at multiple points, you may feel a slight stinging sensation.
Treatment IntervalProfhilo results last approximately 6 months. Initially, 2 sessions at 1 to 2 month intervals are recommended as one set.
After that, 1 to 2 maintenance treatments per year are recommended.
MakeupPoint makeup (avoiding injection sites) is possible from the same day.
Washing / BathingFace washing and showering are possible from the same day, but bathing is allowed from the following day onward.
DowntimeAt our clinic, we use very fine needles and take great care during injection; however, bruising cannot be completely avoided with any needle-based procedure. If bruising does occur, the discoloration will gradually fade over approximately 2 weeks, during which time you may cover it with makeup. If you have an important event coming up, we recommend scheduling your visit at least 2 weeks in advance in case bruising occurs.
Risks- Itching, pain, swelling, bruising, allergic reactions, or infection may occur.
- Insufficient volume may result in a weaker corrective effect.
(Additional injections are possible after 2 weeks, though additional fees will apply.)
PrecautionsThe following individuals cannot receive this treatment:
- Those under 18 years of age
- Those planning to become pregnant within 3 months
- Those who are pregnant, may be pregnant, or are breastfeeding
- Those with skin inflammation or infections
- Those taking anticoagulant or immunosuppressant medications
- Those with severe allergies or autoimmune conditions
- Please refrain from massaging the injection sites for 2 weeks after treatment.
- Please avoid alcohol, vigorous exercise, saunas, and bathing on the day of treatment.

FAQ

When will I see results?

Results become apparent after 3 to 4 weeks as skin remodeling (restructuring) progresses. While results can be seen after a single session, having 2 treatments at 1 to 2 month intervals initially allows you to experience noticeable changes such as a lifting effect, skin tightening, and improved texture.

Treatment Flow

Please refer to this page for the treatment flow.

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