pluryal densify

Pluryal Densify

What is Pluryal Densify?

Pluryal Densify contains three key ingredients: polynucleotides (PN, which boost skin hydration and self-repair ability), non-cross-linked hyaluronic acid (which provides moisture and elasticity), and mannitol (which enhances antioxidant effects). These ingredients work synergistically to maximize each other's effects, delivering long-lasting skin quality improvement.

It is a CE-approved filler series developed by MD Skin Solutions in Luxembourg.
By introducing salmon-derived PN (polynucleotides), which are DNA fragments, surrounding cells are tricked into thinking other cells are damaged, which activates skin regeneration and repair. This enhances wound healing, skin regeneration, skin barrier recovery, hydration, vascular stabilization, and anti-inflammatory activity, resulting in improved skin hydration and elasticity, as well as antioxidant-driven improvement of skin problems and inflammation.
Patented technology completely removes proteins that tend to cause allergic reactions, making it a highly safe formulation with low allergy risk.

Additionally, mannitol has the effect of slowing down the breakdown of hyaluronic acid, which means results last longer compared to conventional skin rejuvenation treatments such as Rejuran.

Key Ingredients of Pluryal Densify:
- Polynucleotides (PN) 20mg
- Non-cross-linked hyaluronic acid 20mg
- Mannitol 80mg

Expected Benefits

Here are the benefits you can expect from Pluryal Densify.

Improved Skin Hydration, Firmness, and Radiance

The self-repair promoting effects of polynucleotides (PN) accelerate the skin's turnover cycle, enhancing the skin's regenerative capacity.

The skin becomes better at retaining moisture, boosting hydration. Dryness and skin problems are reduced, making it easier to maintain healthy skin. Additionally, the elasticity-boosting effect of hyaluronic acid works synergistically to restore firmness and radiance.

Reduction of Fine Lines and Sagging

By promoting collagen production, elasticity improves, firmness is restored from within the skin, and fine lines become less noticeable.

As collagen increases and density improves, the face becomes plumper and sagging becomes less visible. Since the skin retains more moisture and dryness is reduced, it is also effective against fine lines caused by dehydration.

Improvement of Skin Texture Irregularities

The synergistic effect of polynucleotides (PN) and non-cross-linked hyaluronic acid promotes collagen production, which can help reduce the appearance of acne scars, scarring, and other texture irregularities.

Pluryal Densify can also be effective on areas with raised skin such as stretch marks.

Improvement of Redness, Uneven Skin Tone, and Pigmentation

The anti-inflammatory effects of mannitol help suppress skin inflammation, which can improve chronic redness.

Skin turnover is promoted, waste products are expelled, and the complexion becomes more translucent, evening out uneven skin tone. The turnover process also helps shed melanin pigment, which is a cause of pigmentation, gradually improving discoloration over time.

Recommended For

Pluryal Densify is suitable for a wide range of concerns and is recommended for the following:

Those who want to improve sagging
Those who want to boost skin regeneration
Those concerned about acne scars or scarring
Those who want to improve stretch marks
Those who want to treat fine lines
Those who want to improve redness or uneven skin tone
Those troubled by pigmentation or dullness
Those who want to improve atopic dermatitis

Treatment Duration and Schedule

One of the distinctive features of Pluryal Densify is that results can be achieved even after a single treatment. However, since it is a skin cell regeneration treatment, the recommended schedule is once every 3 weeks for 3 to 4 sessions. After that, we recommend maintenance treatments once every 3 months.

Treatment Details

ResultsWithin 1 week to 1 month after injection, skin firmness and elasticity begin to improve, the skin becomes smoother, and wrinkles and sagging are reduced. After 3 months, skin thickness increases, redness and dullness improve, and skin problems decrease due to internal skin strengthening.
Treatment TimeAnesthetic cream application and waiting: approx. 30 minutes
Under-eyes only: approx. 5 minutes
Both cheeks: approx. 5-10 minutes
Forehead: approx. 5 minutes
Full face: 30 minutes
AnesthesiaAnesthetic cream + nitrous oxide sedation recommended
PainAs small amounts are injected at multiple points, you may feel a slight stinging sensation.
Treatment IntervalWhile a single treatment can produce results, repeated sessions provide greater effects.
Initially, 3 sessions at 3-week intervals are recommended. Regular maintenance injections are needed to sustain the results.
MakeupPoint makeup (avoiding injection sites) is possible from the same day.
Washing / BathingFace washing and showering are possible from the same day, but bathing is allowed from the following day onward.
DowntimeAfter injection, small bumps (similar to insect bites) and redness may appear at the injection sites.
This varies by individual, but typically fades by the next day for some, or within about 3 days for others.
If bruising occurs, the discoloration will gradually fade over approximately 2 weeks.
From the following day, you may cover the area with makeup as needed.
If you have an important event coming up, we recommend scheduling your visit at least 2 weeks in advance in case bruising occurs.
Risks- Itching, pain, swelling, bruising, allergic reactions, or infection may occur.
- Insufficient volume may result in a weaker corrective effect.
(Additional injections are possible after 2 weeks, though additional fees will apply.)
PrecautionsThe following individuals cannot receive this treatment:
- Those under 18 years of age
- Those planning to become pregnant within 3 months
- Those who are pregnant, may be pregnant, or are breastfeeding
- Please refrain from massaging the injection sites for 2 weeks after treatment.
- Those with allergies to fish or fish roe
- Those with skin inflammation or infections
- Those taking anticoagulant or immunosuppressant medications
- Those with severe allergies or autoimmune conditions
- Please refrain from massaging the injection sites for 2 weeks.
- Please avoid alcohol, vigorous exercise, saunas, and bathing on the day of treatment.

FAQ

How is it different from Rejuran?

Pluryal Densify causes less pain than Rejuran and the results last longer.
In addition, Densify contains non-cross-linked hyaluronic acid and mannitol alongside polynucleotides, offering greater benefits for skin tone brightening, elasticity improvement, and reduction of redness and skin sensitivity.

Treatment Flow

Please refer to this page for the treatment flow.

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